Anti-PPP1CA antibody [B11-E9]

Anti-PPP1CA antibody [B11-E9]

• 概述

• 产品描述In general, the protein phosphatase (PP) holoenzyme is a trimeric complex composed of a regulatory subunit, a variable subunit and a catalytic subunit. Four major families of protein phosphatase catalytic subunit have been identified, designated PP1, PP2A, PP2B (calcineurin) and PP2C. An additional protein phosphatase catalytic subunit, PPX (also known as PP4) is a putative member of a novel PP family. The PP1 family is comprised of subfamily members PP1α, PP1β and PP1γ, which are MgATP-dependent enzymes. PP1 inactivity is maintained through its association with the inhibitory protein NIPP-1 (nuclear inhibitor of PP1). Phosphorylation of NIPP-1 by cAMP-PK or casein kinase II results in the release of active PP1.
• 产品名称Anti-PPP1CA antibody [B11-E9]
• 分子量38 kDa
• 种属反应性Human
• 验证应用WB
• 抗体类型小鼠单抗
• 免疫原Recombinant protein
• 偶联Non-conjugated

• 性能

• 形态Liquid
• 浓度2 mg/mL.
• 存放说明Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
• 存储缓冲液1*TBS (pH7.4), 1%BSA, Preservative: 0.05% Sodium Azide.
• 亚型IgG1
• 纯化方式Protein A purified.
• 亚细胞定位Nucleus. Cytoplasm.
• 其它名称
  • Alpha isoform serine threonine protein phosphatase PP1alpha 1 catalytic subunit antibody
  • Catalytic subunit antibody
  • EC 3.1.3.16 antibody
  more

• 应用

  WB: 1:500

•  

  

  Fig1: Western blot analysis of PPP1CA on human PPP1CA recombinant protein using anti-PPP1CA antibody at 1/1,000 dilution.

   

  

  Fig2: Western blot analysis of PPP1CA on different cell lysates using anti-PPP1CA antibody at 1/1,000 dilution.
  Positive control:
  Lane 1: A431
  Lane 2: Hela Lane 3: HepG2
  Lane 4: CF-7 Lane
  5:Jurkat
  Lane 6: A549

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