Anti-USP22 antibody [1G4]

Anti-USP22 antibody [1G4]

• 概述

• 产品描述The ubiquitin (Ub) pathway involves three sequential enzymatic steps that facilitate the conjugation of Ub and Ub-like molecules to specific protein substrates. Through the use of a wide range of enzymes that can add or remove ubiquitin, the Ub pathway controls many intracellular processes such as signal transduction, transcriptional activation and cell cycle progression. USP22 (ubiquitin specific peptidase 22), also known as USP3L, is a 525 amino acid protein that contains one UBP-type zinc finger and functions to catalyze the conversion of a ubiquitin C-terminal thioester to free ubiquitin and thiol, a reaction that may influence several cellular processes. Via its catalytic activity, USP22 is thought to play an important role in cell cycle progression and may also serve as a cancer stem cell marker. The gene encoding USP22 maps to human chromosome 17, which comprises over 2.5% of the human genome and encodes over 1,200 genes.
• 产品名称Anti-USP22 antibody [1G4]
• 分子量60 kDa
• 种属反应性Human
• 验证应用WB,IP,IF,ELISA
• 抗体类型小鼠单抗
• 免疫原Amino acids 130-176 mapping within an internal region of USP22 of human origin.
• 偶联Non-conjugated

• 性能

• 形态Liquid
• 浓度2 mg/mL.
• 存放说明Store at +4℃
• 存储缓冲液1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
• 亚型IgG1
• 纯化方式Protein A purified.
• 亚细胞定位Nucleus
• 其它名称
  • Deubiquitinating enzyme 22 antibody
  • KIAA1063 antibody
  • Ubiquitin carboxyl terminal hydrolase 22 antibody
  more

• 应用

  WB: 1:100-1:1,000
  IP: 1-2 μg per 100-500 μg of total protein (1 ml of cell lysate)
  IF: 1:50-1:500
  ELISA: 1:30-1:3000

•  

  

  Fig1: Western blot analysis of USP22 expression in HeLa (A) and Jurkat (B) whole cell lysates.

   

  

  Fig2: Western blot analysis of USP22 expression in Jurkat (A), Caco-2 (B) and F9 (C) whole cell lysates.

特别提示：本公司的所有产品仅可用于科研实验，严禁用于临床医疗及其他非科研用途！