Anti-CD11b antibody [A2-9]

Anti-CD11b antibody [A2-9]

• 概述

• 产品描述Integrin alpha-M/beta-2 is implicated in various adhesive interactions of monocytes, macrophages and granulocytes as well as in mediating the uptake of complement-coated particles. It is identical with CR-3, the receptor for the iC3b fragment of the third complement component. It probably recognizes the R-G-D peptide in C3b. Integrin alpha-M/beta-2 is also a receptor for fibrinogen, factor X and ICAM1. It recognizes P1 and P2 peptides of fibrinogen gamma chain.
• 产品名称Anti-CD11b antibody [A2-9]
• 分子量130kDa
• 种属反应性Human
• 验证应用IHC-P,FC
• 抗体类型小鼠单抗
• 免疫原Recombinant protein within human CD11b 500-750 aa.
• 偶联Non-conjugated

• 性能

• 形态Liquid
• 浓度2 mg/mL.
• 存放说明Store at +4℃ after thawing. Aliquot store at -20℃. Avoid repeated freeze / thaw cycles.
• 存储缓冲液1*PBS (pH7.4), 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
• 亚型IgG2b
• 纯化方式Protein A purified.
• 亚细胞定位Membrane
• 其它名称
  • antigen CD11b (p170) antibody
  • Antigen CD11b p170 antibody
  • CD11 antigen like family member B antibody
  more

• 应用

  IHC-P: 1:200
  FC: 1:200

•  

  

  Fig1: Immunohistochemical analysis of paraffin-embedded human tonsil tissue using anti-CD11b antibody. Counter stained with hematoxylin.

   

  

  Fig2: Immunohistochemical analysis of paraffin-embedded human spleen tissue using anti-CD11b antibody. Counter stained with hematoxylin.

   

  

  Fig3: Flow cytometric analysis of Raji cells with CD11b antibody at 1/100 dilution (blue) compared with an unlabelled control (cells without incubation with primary antibody; red). Goat anti mouse IgG (FITC) was used as the secondary antibody.

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