Anti-β-Catenin antibody
-
概述
- 产品描述β-Catenin is a multifunctional adaptor protein involved in cadherin-mediated cell–cell adhesion and in responding to the activation of several signal transduction pathways. CK1 phosphorylates β-catenin on Ser45. This phosphorylation event primes β-catenin for subsequent phosphorylation by GSK-3. GSK-3β destabilizes β-catenin by phosphorylating it at Ser33, Ser37 and Thr41.). Mutations in β-Catenin have been implicated in its accumulation and various forms of carcinomas.
- 产品名称Anti-β-Catenin antibody
- 分子量85 kDa
- 种属反应性Human,Mouse,Rat, Zebrafish
- 验证应用WB, ICC, IHC-P
- 抗体类型兔多抗
- 免疫原peptide
- 偶联Non-conjugated
-
性能
- 形态Liquid
- 浓度1 mg/mL.
- 存放说明Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
- 存储缓冲液1*PBS (pH7.4), 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
- 亚型IgG
- 纯化方式Immunogen affinity purified
- 亚细胞定位Cell membrane, perinuclear region
- 数据链接Q02248
- 其它名称Beta catenin antibody
Beta-catenin antibody
Cadherin associated protein antibody
Catenin (cadherin associated protein), beta 1, 88kDa antibody
Catenin beta 1 antibody
Catenin beta-1 antibody
CATNB antibody
CHBCAT antibody
CTNB1_HUMAN antibody
CTNNB antibody
CTNNB1 antibody
DKFZp686D02253 antibody
FLJ25606 antibody
FLJ37923 antibody
OTTHUMP00000162082 antibody
OTTHUMP00000165222 antibody
OTTHUMP00000165223 antibody
OTTHUMP00000209288 antibody
OTTHUMP00000209289 antibody
more
-
-
Fig1: Western blot analysis on cell lysates using anti-β-Catenin polyclonal antibody
Fig2: Western blot analysis of β-Catenin on hybrid fish (crucian-carp) heart tissue lysate using anti-β-Catenin antibody at 1/500 dilution.
Fig3: ICC staining β-Catenin (green) in Hela cells. Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
特别提示：本公司的所有产品仅可用于科研实验，严禁用于临床医疗及其他非科研用途！
