Anti-4E-BP1 antibody
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概述
- 产品描述EIF4EBP1 encodes one member (eukaryotic translation initiation factor 4E binding protein 1) of a family of translation repressor proteins. The protein directly interacts with eukaryotic translation initiation factor 4E (eIF4E), which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5' end of mRNAs. Interaction of this protein with eIF4E inhibits complex assembly and represses translation. This protein is phosphorylated in response to various signals including UV irradiation and insulin signaling, resulting in its dissociation from eIF4E and activation of mRNA translation.
- 产品名称Anti-4E-BP1 antibody
- 分子量12 kDa
- 种属反应性Mouse, Rat, Monkey
- 验证应用WB, IHC-P
- 抗体类型兔多抗
- 免疫原The antiserum was produced against synthesized peptide derived from mouse 4E-BP1. AA range:35-84
- 偶联Non-conjugated
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性能
- 形态Liquid
- 浓度1 mg/mL.
- 存放说明Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
- 存储缓冲液Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- 亚型IgG
- 纯化方式Immunogen affinity purified.
- 其它名称EIF4EBP1 antibody; Eukaryotic translation initiation factor 4E-binding protein 1 antibody; 4E-BP1 antibody; eIF4E-binding protein 1 antibody; Phosphorylated heat- and acid-stable protein regulated by insulin 1 antibody; PHAS-I antibody;
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应用
WB: 1:500-1:2000
IHC-P: 1:100-1:300
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Fig1: Western Blot analysis of various cells using 4E-BP1 Polyclonal Antibody diluted at 1:500
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