Anti-UBE3C antibody
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概述
- 产品描述E3 ubiquitin-protein ligase that accepts ubiquitin from the E2 ubiquitin-conjugating enzyme UBE2D1 in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. It can target itself for ubiquitination in vitro and may promote its own degradation in vivo. miscellaneous:A cysteine residue is required for ubiquitin-thioester formation. pathway:Protein modification; protein ubiquitination. Contains 1 HECT (E6AP-type E3 ubiquitin-protein ligase) domain. Contains 1 IQ domain. subunit:Interacts with 26S proteasomes. Binds CAND2. tissue specificity:Highly expressed in skeletal muscle. Detected at much lower levels in kidney and pancreas.
- 产品名称Anti-UBE3C antibody
- 分子量125 kDa
- 种属反应性Human
- 验证应用WB
- 抗体类型兔多抗
- 免疫原Synthesized peptide derived from the Internal region of human UBE3C.
- 偶联Non-conjugated
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性能
- 形态Liquid
- 浓度1 mg/mL.
- 存放说明Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
- 存储缓冲液Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- 亚型IgG
- 纯化方式Immunogen affinity purified.
- 其它名称
- UBE3C antibody; KIAA0010 antibody; KIAA10 antibody; Ubiquitin-protein ligase E3C antibody; HectH2 antibody;
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Fig1: Western Blot analysis of various cells using UBE3C Polyclonal Antibody. Secondary antibody(catalog#:HA1001) was diluted at 1:20000 cells nucleus extracted by Minute TM Cytoplasmic and Nuclear Fractionation kit (SC-003,Inventbiotech,MN,USA).
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