Anti-MAP3K8 antibody

Anti-MAP3K8 antibody

• 概述

• 产品描述Required for TLR4 activation of the MEK/ERK pathway. Able to activate NF-kappa-B 1 by stimulating proteasome-mediated proteolysis of NF-kappa-B 1/p105. Plays a role in the cell cycle. The longer form has some transforming activity, although it is much weaker than the activated cot oncoprotein.
• 产品名称Anti-MAP3K8 antibody
• 分子量53 KDa
• 种属反应性Human,Mouse,Rat,Chicken,Dog,Cow,Horse,Rabbit
• 验证应用WB
• 抗体类型兔多抗
• 免疫原KLH conjugated synthetic peptide derived from human MAP3K8/TPL2 121-220/468
• 偶联Non-conjugated

• 性能

• 形态Liquid
• 浓度1 mg/mL.
• 存放说明Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20℃. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4℃.
• 存储缓冲液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
• 亚型IgG
• 纯化方式affinity purified by Protein A
• 亚细胞定位Cytoplasm.
  
• 其它名称c COT
  Cancer Osaka thyroid oncogene
  Cancer Osaka thyroid oncogene
  CCOT
  COT
  COT proto oncogene serine/threonine protein kinase
  EST
  ESTF
  Ewing sarcoma transformant
  FLJ10486
  M3K8_HUMAN
  MAP3K 8
  MAP3K8
  Mitogen activated protein kinase kinase kinase 8
  Mitogen-activated protein kinase kinase kinase 8
  Proto oncogene cCot
  Proto-oncogene c-Cot
  Serine/threonine protein kinase cot
  Serine/threonine-protein kinase cot
  TPL 2
  TPL-2
  TPL2
  Tumor progression locus 2.
  more

• 应用

  WB:1:500-2000

•  

  

  Fig1: Sample:
  Lane 1: Heart (Mouse) Lysate at 30 ug
  Lane 2: Brain (Mouse) Cell Lysate at 30 ug
  Primary: Anti-MAP3K8/TPL2at 1/200 dilution
  Secondary: HRP conjugated Goat-Anti-rabbit IgG (bs-0295G-HRP) at 1/3000 dilution
  Predicted band size: 53kD
  Observed band size: 50kD

   

  

  Fig2: Sample:
  Thymus (Mouse) Lysate at 40 ug
  Primary: Anti-MAP3K8  at 1/1000 dilution
  Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
  Predicted band size: 53 kD
  Observed band size: 53 kD

   

  

  Fig3: Sample:
  Spleen (Mouse) Lysate at 40 ug
  Primary: Anti-MAP3K8t 1/1000 dilution
  Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
  Predicted band size: 53 kD
  Observed band size: 53 kD

特别提示：本公司的所有产品仅可用于科研实验，严禁用于临床医疗及其他非科研用途！