Anti-MAP3K9 antibody
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概述
- 产品描述Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. Plays an important role in the cascades of cellular responses evoked by changes in the environment. Once activated, acts as an upstream activator of the MKK/JNK signal transduction cascade through the phosphorylation of MAP2K4/MKK4 and MAP2K7/MKK7 which in turn activate the JNKs. The MKK/JNK signaling pathway regulates stress response via activator protein-1 (JUN) and GATA4 transcription factors. Plays also a role in mitochondrial death signaling pathway, including the release cytochrome c, leading to apoptosis.
- 产品名称Anti-MAP3K9 antibody
- 分子量122 KDa
- 种属反应性Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep
- 验证应用WB
- 抗体类型兔多抗
- 免疫原KLH conjugated synthetic peptide derived from human MAP3K9 451-550/1104
- 偶联Non-conjugated
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性能
- 形态Liquid
- 浓度1 mg/mL.
- 存放说明Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20℃. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4℃.
- 存储缓冲液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 亚型IgG
- 纯化方式affinity purified by Protein A
- 其它名称MLK1
M3K9_HUMAN
Map3k9
MEKK9
Mitogen activated protein kinase kinase kinase 9
Mitogen-activated protein kinase kinase kinase 9
Mixed lineage kinase 1 (tyr and ser/thr specificity)
Mixed lineage kinase 1
PRKE1.
more
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Fig1: Sample:
MCF-7(Human) Cell Lysate at 30 ug
Primary: Anti-MAP3K9at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 122 kD
Observed band size: 122 kD
特别提示：本公司的所有产品仅可用于科研实验，严禁用于临床医疗及其他非科研用途！
