Anti-VEGF Receptor 2 antibody
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概述
- 产品描述Three cell membrane receptor tyrosine kinases, Flt (also designated VEGF-R1) (1-3), Flk-1 (also designated VEGF-R2) (4-6) and Flt-4, putatively involved in the growth of endothelial cells, are characterized by the presence of seven immunoglobulin-like sequences in their extracellular domain. These receptors exhibit high degrees of sequence relatedness to each other as well as lesser degrees of relatedness to the class III receptors including CSF-1/Fms, PDGR, SLFR/Kit and Flt-3/Flk-2. Two members of this receptor class, Flt-1 and Flk-1, have been shown to represent high affinity receptors for vascular endothelial growth factors (VEGFs) (3,5). On the basis of structural similarity to Flt and Flk-1, it has been speculated that Flt-4 might represent a third receptor for either VEGF or a VEGF-related ligand.
- 产品名称Anti-VEGF Receptor 2 antibody
- 分子量152 kDa
- 种属反应性Human,Mouse,Rat
- 验证应用ICC,IHC-P,WB,FC
- 抗体类型兔多抗
- 免疫原Peptide
- 偶联Non-conjugated
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性能
- 形态Liquid
- 浓度1 mg/mL.
- 存放说明Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
- 存储缓冲液1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
- 亚型IgG
- 纯化方式Peptide affinity purified
- 亚细胞定位Nucleus. Membrane. Secreted.
- 其它名称CD309 antibody
CD309 antigen antibody
EC 2.7.10.1 antibody
Fetal liver kinase 1 antibody
FLK-1 antibody
FLK1 antibody
FLK1, mouse, homolog of antibody
Kdr antibody
Kinase insert domain receptor (a type III receptor tyrosine kinase) antibody
Kinase insert domain receptor antibody
KRD1 antibody
Ly73 antibody
Protein tyrosine kinase receptor FLK1 antibody
Protein-tyrosine kinase receptor flk-1 antibody
soluble VEGFR2 antibody
Tyrosine kinase growth factor receptor antibody
Vascular endothelial growth factor receptor 2 antibody
VEGFR 2 antibody
VEGFR antibody
VEGFR-2 antibody
VEGFR2 antibody
VGFR2_HUMAN antibody
more
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应用
ICC: 1:50-1:200
IHC-P: 1:50-1:200
WB: 1:500
FC: 1:50-1:100
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Fig1: ICC staining VEGF Receptor 2 in HepG2 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
Fig2: ICC staining VEGF Receptor 2 in HUVEC cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
Fig3: ICC staining VEGF Receptor 2 in PMVEC cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
Fig4: Immunohistochemical analysis of paraffin-embedded rat kidney tissue using anti-VEGF Receptor 2 antibody. Counter stained with hematoxylin.
Fig5: Immunohistochemical analysis of paraffin-embedded human breast tissue using anti-VEGF Receptor 2 antibody. Counter stained with hematoxylin.
Fig6: Immunohistochemical analysis of paraffin-embedded mouse kidney tissue using anti-VEGF Receptor 2 antibody. Counter stained with hematoxylin.
Fig7: Immunohistochemical analysis of paraffin-embedded human kidney tissue using anti-VEGF Receptor 2 antibody. Counter stained with hematoxylin.
Fig8: Flow cytometric analysis of HUVEC cells with VEGF Receptor 2 antibody at 1/100 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black). Alexa Fluor 488-conjugated goat anti rabbit IgG was used as th
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