Anti-Fetuin A/AHSG antibody
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概述
- 产品描述alpha-2-HS-glycoprotein (AHSG) also known as fetuin-A is a protein that in humans is encoded by the AHSG gene. Fetuin-A belongs to the fetuin class of plasma binding proteins and is more abundant in fetal than adult blood. Alpha2-HS glycoprotein, a glycoprotein present in the serum, is synthesized by hepatocytes. The AHSG molecule consists of two polypeptide chains, which are both cleaved from a proprotein encoded from a single mRNA. It is involved in several functions, such as endocytosis, brain development and the formation of bone tissue. The protein is commonly present in the cortical plate of the immature cerebral cortex and bone marrow hemopoietic matrix, and it has therefore been postulated that it participates in the development of the tissues. However, its exact significance is still obscure. The choroid plexus is an established extrahepatic expression site. The mature circulating AHSG molecule consists of two polypeptide chains, which are both cleaved from a proprotein encoded from a single mRNA. Multiple post-translational modifications have been reported. Thus AHSG is a secreted partially phosphorylated glycoprotein with complex proeolytic processing that circulates in blood and extracellular fluids. In the test tube AHSG can bind multiple ligands and therefore has been claimed to be involved in several functions, such as endocytosis, brain development and the formation of bone tissue. Most of these functions await confirmation in vivo. Fetuins are carrier proteins like albumin. Fetuin-A forms soluble complexes with calcium and phosphate and thus is a carrier of otherwise insoluble calcium phosphate.
- 产品名称Anti-Fetuin A/AHSG antibody
- 分子量31/40 KDa
- 种属反应性Human,Mouse,Rat,Dog,Cow,Horse,Rabbit,Sheep
- 验证应用WB
- 抗体类型兔多抗
- 免疫原KLH conjugated synthetic peptide derived from human Alpha-2-HS-glycoprotein chain A. 201-300/367
- 偶联Non-conjugated
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性能
- 形态Liquid
- 浓度1 mg/mL.
- 存放说明Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
- 存储缓冲液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 亚型IgG
- 纯化方式Affinity purified by Protein A.
- 亚细胞定位Secreted.
- 其它名称Fetuin-A
59 kDa bone sialic acid containing protein
A2HS
Aa2 066
AHS
AHSG
Alpha 2 HS glycoprotein
Alpha 2 HS glycoprotein chain A
Alpha 2 Z globulin
Alpha 2HS glycoprotein
alpha2 Heremans Schmid glycoprotein
Asialofetuin
Ba alpha 2 glycoprotein
BSP
Countertrypin
FETUA
Fetuin A
Fetuin, mouse, homolog of
FetuinA
Glycoprotein PP63
HSGA
pp63
Alpha-2-HS-glycoprotein chain A
more
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Fig1: Sample: liver (mouse)cell Lysate at 40 ug
Primary: Anti- Fetuin A/AHSG at 1/300 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 31kD
Observed band size: 34 kD
特别提示：本公司的所有产品仅可用于科研实验，严禁用于临床医疗及其他非科研用途！
