Anti-CRMP2 antibody
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概述
- 产品描述Collapsin response mediator proteins (CRMPs), including CRMP-1 (DRP-1), CRMP-2 (DRP-2 or TOAD64), CRMP-3 (DRP-4), CRMP-4 (DRP-3) and CRMP-5 (DRP-5), mediate signal transduction after exposure of neural cells to the axon guidance molecule Semaphorin 3A (SEMA3A)/collapsin. CRMPs are present in the developing cerebral cortex and neocortical neurons and are responsive to SEMA3A. In the adult brain, the expression of CRMPs is dramatically downregulated. However, they remain expressed in structures that retain their capacity for differentiation and plasticity. CRMP-2 is involved in axonal growth and guidance. The human CRMP-2 gene maps to 8p21.2, a chromosomal region that has been previously shown to have a significant linkage to schizophrenia and to several deficit symptoms of schizophrenia.
- 产品名称Anti-CRMP2 antibody
- 分子量62 kDa
- 种属反应性Human,Mouse
- 验证应用WB,ICC,IHC-P
- 抗体类型兔多抗
- 免疫原Recombinant protein with Human CRMP2 aa 100-300.
- 偶联Non-conjugated
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性能
- 形态Liquid
- 浓度1 mg/mL.
- 存放说明Store at +4℃ after thawing. Aliquot store at -20℃. Avoid repeated freeze / thaw cycles.
- 存储缓冲液1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
- 亚型IgG
- 纯化方式Protein affinity purified.
- 亚细胞定位Cytosol. Cytoskeleton. Membrane.
- 其它名称Collapsin response mediator protein 2 antibody
Collapsin response mediator protein antibody
Collapsin response mediator protein hCRMP 2 antibody
CRAM antibody
CRMP 2 antibody
CRMP-2 antibody
CRMP2 antibody
DHPRP 2 antibody
DHPRP2 antibody
Dihydropyrimidinase 2 antibody
Dihydropyrimidinase like 2 antibody
Dihydropyrimidinase like 2 long form antibody
Dihydropyrimidinase related protein 2 antibody
Dihydropyrimidinase-related protein 2 antibody
DPYL 2 antibody
DPYL2 antibody
DPYL2_HUMAN antibody
DPYSL 2 antibody
Dpysl2 antibody
DRP-2 antibody
DRP2 antibody
Musunc 33 antibody
Musunc33 antibody
N2A3 antibody
TOAD 64 antibody
TOAD64 antibody
ULIP 2 protein antibody
ULIP-2 antibody
Ulip2 antibody
Unc-33-like phosphoprotein 2 antibody
more
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应用
WB: 1:1,000-1:5,000
ICC: 1:50-1:200
IHC-P: 1:50-1:200
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Fig1: Western blot analysis of CRMP2 on different lysates using anti-CRMP2 antibody at 1/5,000 dilution.
Positive control:
Lane 1: Mouse brain tissue Lane 2: SH-SY-5Y
Fig2: ICC staining CRMP2 in A549 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
Fig3: ICC staining CRMP2 in SH-SY-5Y cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
Fig4: ICC staining CRMP2 in SiHa cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
Fig5: Immunohistochemical analysis of paraffin-embedded human tonsil tissue using anti-CRMP2 antibody. Counter stained with hematoxylin.
Fig6: Immunohistochemical analysis of paraffin-embedded human colon tissue using anti-CRMP2 antibody. Counter stained with hematoxylin.
Fig7: Immunohistochemical analysis of paraffin-embedded human breast cancer tissue using anti-CRMP2 antibody. Counter stained with hematoxylin.
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