Anti-CTGF antibody
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概述
- 产品描述Connective tissue growth factor (CTGF, also known as hypertrophic chondrocyte-specific gene product 24 or Hcs24), is a member of the CCN family of immediate early proteins, which are involved in cell proliferation, migration and matrix production. CTGF is a cysteine-rich peptide that is secreted by endothelial cells, fibroblasts, smooth muscle cells and myofibroblasts. Its expression is increased in various human and animal fibrotic diseases. Specifically, CTGF has been observed to be strongly upregulated in human proliferative and fibrogenic renal disease. In addition, CTGF is a growth factor for vascular smooth muscle cells (VSMC) and may play a similar role in promoting VSMC growth and migration in vitro.
- 产品名称Anti-CTGF antibody
- 分子量38 kDa
- 种属反应性Human,Mouse
- 验证应用WB,ICC,IHC-P
- 抗体类型兔多抗
- 免疫原Recombinant protein with human CTGF aa 150-300.
- 偶联Non-conjugated
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性能
- 形态Liquid
- 浓度1 mg/mL.
- 存放说明Store at +4℃ after thawing. Aliquot store at -20℃. Avoid repeated freeze / thaw cycles.
- 存储缓冲液1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
- 亚型IgG
- 纯化方式Protein affinity purified.
- 亚细胞定位Extracellular region or secreted.
- 其它名称CCN 2 antibody
CCN family member 2 antibody
CCN2 antibody
Connective tissue growth factor antibody
Ctgf antibody
CTGF_HUMAN antibody
Hcs 24 antibody
Hcs24 antibody
Hypertrophic chondrocyte specific protein 24 antibody
Hypertrophic chondrocyte-specific gene product 24 antibody
Hypertrophic chondrocyte-specific protein 24 antibody IBP-8 antibody
IGF-binding protein 8 antibody
IGFBP-8 antibody
IGFBP8 antibody
Insulin like Growth Factor Binding Protein 8 antibody
Insulin-like growth factor-binding protein 8 antibody
MGC102839 antibody
NOV 2 antibody
NOV2 antibody
more
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应用
WB: 1:500
ICC: 1:50-1:200
IHC-P: 1:50-1:200
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Fig1: Western blot analysis of CTGF on mouse smooth muscle tissue lysate using anti-CTGF antibody at 1/500 dilution.
Fig2: ICC staining CTGF in HepG2 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
Fig3: ICC staining CTGF in HUVEC cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
Fig4: ICC staining CTGF in SiHa cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
Fig5: Immunohistochemical analysis of paraffin-embedded human appendix tissue using anti-CTGF antibody. Counter stained with hematoxylin.
Fig6: Immunohistochemical analysis of paraffin-embedded human thyroid gland cancer tissue using anti-CTGF antibody. Counter stained with hematoxylin.
Fig7: Immunohistochemical analysis of paraffin-embedded human uterus tissue using anti-CTGF antibody. Counter stained with hematoxylin.
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