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Anti-CD108 antibody

Anti-CD108 antibody
别名: CD108
适用物种: Human,Mouse,Rat,Dog,Cow  
验证应用: WB,IHC-P  
种属: 兔多抗  
储存条件: -20℃ 
Anti-CD108 antibody
货号 规格 可用库存 销售价(RMB) 您的折扣价(RMB) 购买数量
ZY6905-75R-50 μl 兔多抗 现货 1500.00 1500
ZY6905-75R-100 μl 兔多抗 现货 2500.00 2500
熔点:
密度:
储存条件: -20℃

 

Anti-CD108 antibody

 

  • 概述

  • 产品描述Plays an important role in integrin-mediated signaling and functions both in regulating cell migration and immune responses. Promotes formation of focal adhesion complexes, activation of the protein kinase PTK2/FAK1 and subsequent phosphorylation of MAPK1 and MAPK3. Promotes production of proinflammatory cytokines by monocytes and macrophages. Plays an important role in modulating inflammation and T cell-mediated immune responses. Promotes axon growth in the embryonic olfactory bulb. Promotes attachment, spreading and dendrite outgrowth in melanocytes.

  • 产品名称Anti-CD108 antibody

  • 分子量66 KDa

  • 种属反应性Human,Mouse,Rat,Dog,Cow

  • 验证应用WB,IHC-P

  • 抗体类型兔多抗

  • 免疫原KLH conjugated synthetic peptide derived from human Sema7A 351-450/666

  • 偶联Non-conjugated

  • 性能

  • 形态Liquid

  • 浓度1 mg/mL.

  • 存放说明Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20℃. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4℃.

  • 存储缓冲液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

  • 亚型IgG

  • 纯化方式affinity purified by Protein A

  • 亚细胞定位Cell membrane; Lipid-anchor, GPI-anchor; Extracellular side. Note=Detected in a punctate pattern on the cell membrane of basal and supra-basal skin keratinocytes.

  •  

  • ​其它名称semaphorin 7A
    CD 108
    CD108
    CD108 antigen
    CDw108
    H Sema K1
    H Sema L
    JMH
    JMH blood group antigen
    John Milton Hagen blood group H Sema K1
    John Milton Hargen human blood group Ag
    MGC126692
    MGC126696
    Sema domain immunoglobulin domain (Ig) and GPI membrane anchor 7A
    Sema L
    Sema7a
    SEMAK1
    SEMAL
    Semaphorin 7A GPI membrane anchor
    Semaphorin K1
    Semaphorin L
    Semaphorin7a
    SEM7A_HUMAN.

    more
  • 应用

    WB:1:500-2000
    IHC-P:1:400-800

  •  

    Fig1: Sample:
    Lane 1: Brain (Mouse) Lysate at 30 ug
    Lane 2: Lung (Mouse) Lysate at 30 ug
    Primary: Anti-Sema7A/CD10 at 1:200 dilution;
    Secondary: HRP conjugated Goat Anti-Rabbit IgG(bs-0295G-HRP) at 1: 3000 dilution;
    Predicted band size : 66kD
    Observed band size : 66kD

     

    Fig2: Paraformaldehyde-fixed, paraffin embedded (human liver carcinoma); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37℃ for 30min; Antibody incubation with (CD108) Polyclonal Antibody, Unconjugated  at 1:400 overnight at 4℃, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.

     

    Fig3: Sample:
    Cerebrum (Mouse) Lysate at 40 ug
    Lung (Mouse) Lysate at 40 ug
    Primary: Anti-CD108  at 1/1000 dilution
    Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
    Predicted band size: 66 kD
    Observed band size: 63 kD

     

    Fig4: Sample:
    Skin (Mouse) Lysate at 40 ug
    Skin(Rat) Lysate at 40 ug
    Primary: Anti-CD108  at 1/1000 dilution
    Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
    Predicted band size: 66 kD
    Observed band size: 66 kD

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