Anti-ROR alpha antibody

Anti-ROR antibody

• 概述

• 产品描述Orphan nuclear receptor. Binds DNA as a monomer to hormone response elements (HRE) containing a single core motif half-site preceded by a short A-T-rich sequence. This isomer binds to the consensus sequence 5'-[AT][TA]A[AT][CGT]TAGGTCA-3'. Regulates a number of genes involved in lipid metabolism such as apolipoproteins AI, APOA5, CIII, CYP71 and PPARgamma, in cerebellum and photoreceptor development including PCP2, OPN1SW, OPN1SM AND ARR3, in circadian rhythm with BMAL1, and skeletal muscle development with MYOD1. Possible receptor for cholesterol or one of its derivatives.
• 产品名称Anti-ROR alpha antibody
• 分子量59 KDa
• 种属反应性Human,Mouse,Rat,Chicken,Dog,Pig,Cow,Rabbit,Sheep
• 验证应用WB
• 抗体类型兔多抗
• 免疫原KLH conjugated synthetic peptide derived from human ROR alpha 151-250/523
• 偶联Non-conjugated

• 性能

• 形态Liquid
• 浓度1 mg/mL.
• 存放说明Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20℃. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4℃.
• 存储缓冲液Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4
• 亚型IgG
• 纯化方式affinity purified by Protein A
• 亚细胞定位Nucleus.
• 其它名称NR1F1
  Nuclear receptor ROR-alpha
  Nuclear receptor RZR-alpha
  Nuclear receptor subfamily 1 group F member 1
  RAR-related orphan receptor A
  Retinoid-related orphan receptor-alpha
  Rora
  RORA_HUMAN
  RZR-ALPHA
  RZRA.
  more

• 应用

  WB:1:500-2000

•  

  

  Fig1: Sample: A431(human) Cell Lysate at 40 ug
  Primary: Anti-ROR alphaat 1/300 dilution
  Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
  Predicted band size: 59 kD
  Observed band size: 59 kD

   

  

  Fig2: Sample: Muscle (Mouse) Lysate at 40 ug
  Primary: Anti-ROR alphaat 1/300 dilution
  Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
  Predicted band size: 59 kD
  Observed band size: 59 kD

   

  

  Fig3: Sample: Jurkat (Human) Cell Lysate at 40 ug
  Primary: Anti-ROR alphaat 1/300 dilution
  Secondary: IRDye800CW Goat Anti-RabbitIgG at 1/20000 dilution
  Predicted band size: 59kD
  Observed band size: 59 kD

特别提示：本公司的所有产品仅可用于科研实验，严禁用于临床医疗及其他非科研用途！