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Anti-TLR7 antibody
产品描述Members of the Toll-like receptor (TLR) family, named for the closely related Toll receptor in Drosophila, play a pivotal role in innate immune responses. TLRs recognize conserved motifs found in various pathogens and mediate defense responses. TLR7, 8 and 9 form a group of structurally related TLR family members that are localized to intracellular endosomes . TLR7 shows highest expression in lung, placenta, and spleen. TLR7 mediates responses to a class of synthetic compounds, including imidazoquinolines, guanosine-based drugs that induce anti-viral responses.
产品名称Anti-TLR7 antibody
分子量140 kDa
种属反应性Human,Mouse,Rat
验证应用WB,IHC-P
抗体类型兔多抗
免疫原peptide
偶联Non-conjugated
形态Liquid
浓度1 mg/mL.
存放说明Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
存储缓冲液1*PBS (pH7.4), 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
亚型IgG
纯化方式Peptide affinity purified
亚细胞定位Endoplasmic reticulum membrane.
其它名称
WB: 1:1,000
IHC-P: 1:200
Fig1: Western blot analysis of TLR7 on different cell lysates using anti-TLR7 antibody at 1/1000 dilution.
Positive control:
Lane 1: Raji
Lane 2: Daudi
Lane 3: Jurkat
Lane 4: THP-1
Fig2: Immunohistochemical analysis of paraffin-embedded human tonsil tissue using anti-TLR7 antibody. Counter stained with hematoxylin.
Fig3: Immunohistochemical analysis of paraffin-embedded human lung tissue using anti-TLR7 antibody. Counter stained with hematoxylin.
Fig4: Immunohistochemical analysis of paraffin-embedded mouse lung tissue using anti-TLR7 antibody. Counter stained with hematoxylin.
特别提示：本公司的所有产品仅可用于科研实验，严禁用于临床医疗及其他非科研用途！
