Anti-MATER antibody
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概述
- 产品描述NLRP5, short for NOD-like receptor family pyrin domain containing 5, is an intracellular protein that plays a role in early embryogenesis. NLRP5 is also known as NACHT, LRR and PYD domains-containing protein 5 (NALP5), Mater protein homolog (MATER), PYPAF8, PAN11, and CLR19.8, and is one of 14 pyrin domain containing members of the NOD-like receptor family of cytoplasmic receptors known to mammals. Conserved oocyte-specific expression of NLRP5 is consistent among many mammalian species. As a member of the subcortical maternal complex (SCMC), it plays an essential role for zygotes to progress beyond the first embryonic cell divisions. NLRP5 also localizes to the nuclear envelope and mitochondria in germinal vesicle oocytes, suggesting a possible role in mitochondrial function.
- 产品名称Anti-MATER antibody
- 分子量134 kDa
- 种属反应性Human,Mouse
- 验证应用ICC
- 抗体类型兔多抗
- 免疫原peptide
- 偶联Non-conjugated
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性能
- 形态Liquid
- 浓度1 mg/mL.
- 存放说明Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
- 存储缓冲液1*PBS (pH7.4), 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
- 亚型IgG
- 纯化方式Peptide affinity purified
- 亚细胞定位Cytoplasm, nucleus, mitochondrion.
- 其它名称CLR19.8 antibody
MATER antibody
Mater protein homolog antibody
Maternal antigen that embryos require antibody
NACHT, leucine rich repeat and PYD containing 5 antibody
NACHT, LRR and PYD domains-containing protein 5 antibody
NALP5_HUMAN antibody
NLR family, pyrin domain containing 5 antibody
NLRP5 antibody
Nucleotide-binding oligomerization domain, leucine rich repeat and pyrin domain containing 5 antibody
PAN11 antibody
PYPAF8 antibody
more
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Fig1: ICC staining MATER in mouse blastocyst and 2-cell stage embryo (red). Cells were incubated overnight at 4
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