Anti-BRSK1 antibody
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概述
- 产品描述catalytic activity:ATP + a protein = ADP + a phosphoprotein. cofactor:Magnesium. enzyme regulation:Activated by phosphorylation on Thr-205 by STK11 in complex with STE20-related adapter-alpha (STRAD alpha) pseudo kinase and CAB39. Required for the polarization of forebrain neurons which endows axons and dendrites with distinct properties, possibly by locally regulating phosphorylation of microtubule-associated proteins (By similarity). May be involved in the regulation of G2/M arrest in response to UV- or methyl methane sulfonate (MMS)-induced, but not IR-induced, DNA damage. Phosphorylates WEE1 and CDC25B in vitro and CDC25C in vitro and in vivo. Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. AMPK subfamily. Contains 1 protein kinase domain. Contains 1 UBA domain. subcellular location:Nuclear in the absence of DNA damage. Translocated to the nucleus in response to UV- or MMS-induced DNA damage. tissue specificity:Widely expressed, with highest levels in brain and testis. Protein levels remain constant throughout the cell cycle.
- 产品名称Anti-BRSK1 antibody
- 分子量87 kDa
- 种属反应性Human, Mouse
- 验证应用WB, IF
- 抗体类型兔多抗
- 免疫原The antiserum was produced against synthesized peptide derived from human BRSK1. AA range:361-410
- 偶联Non-conjugated
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性能
- 形态Liquid
- 浓度1 mg/mL.
- 存放说明Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
- 存储缓冲液Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- 亚型IgG
- 纯化方式Immunogen affinity purified.
- 其它名称BRSK1 antibody; KIAA1811 antibody; SAD1 antibody; SADB antibody; Serine/threonine-protein kinase BRSK1 antibody; Brain-selective kinase 1 antibody; Brain-specific serine/threonine-protein kinase 1 antibody; BR serine/threonine-protein kinase 1 antibody; Serine/threonine-protein kinase SAD-B antibody; Synapses of Amphids antibody;
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应用
WB: 1:500-1:2000
IF: 1:100-1:500
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Fig1: Western Blot analysis of various cells using BRSK1 Polyclonal Antibody
特别提示:本公司的所有产品仅可用于科研实验,严禁用于临床医疗及其他非科研用途!