Anti-Adducin α/β antibody
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概述
- 产品描述Adducins are a family of cytoskeleton proteins encoded by three genes (alpha, beta, gamma). Adducin is a heterodimeric protein that consists of related subunits, which are produced from distinct genes but share a similar structure. Alpha- and beta-adducin include a protease-resistant N-terminal region and a protease-sensitive, hydrophilic C-terminal region. Alpha- and gamma-adducins are ubiquitously expressed. In contrast, beta-adducin is expressed at high levels in brain and hematopoietic tissues. Adducin binds with high affinity to Ca(2+)/calmodulin and is a substrate for protein kinases A and C. Alternative splicing results in multiple variants encoding distinct isoforms; however, not all variants have been fully described.
- 产品名称Anti-Adducin α/β antibody
- 分子量80 kDa
- 种属反应性Human, Mouse, Rat
- 验证应用WB, IHC-P, IP,IF
- 抗体类型兔多抗
- 免疫原The antiserum was produced against synthesized peptide derived from human ADD1. AA range:688-737
- 偶联Non-conjugated
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性能
- 形态Liquid
- 浓度1 mg/mL.
- 存放说明Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
- 存储缓冲液Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- 亚型IgG
- 纯化方式Immunogen affinity purified.
- 其它名称ADD1 antibody; ADDA antibody; Alpha-adducin antibody; Erythrocyte adducin subunit alpha antibody; ADD2 antibody; ADDB antibody; Beta-adducin antibody; Erythrocyte adducin subunit beta antibody;
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应用
WB: 1:500-1:2000
IHC-P: 1:100-1:300
Immunoprecipitation: 2-5 ug/mg lysate
IF: 1:100-1:500
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Fig1: Western Blot analysis of various cells using Adducin α/β Polyclonal Antibody diluted at 1:1000
特别提示:本公司的所有产品仅可用于科研实验,严禁用于临床医疗及其他非科研用途!