Anti-AMPKγ1/2/3 antibody
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概述
- 产品描述The protein encoded by this gene is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This subunit is one of the gamma regulatory subunits of AMPK. Alternatively spliced transcript variants encoding distinct isoforms have been observed.
- 产品名称Anti-AMPKγ1/2/3 antibody
- 分子量38 kDa
- 种属反应性Human,Mouse,Rat
- 验证应用WB,IF
- 抗体类型兔多抗
- 免疫原The antiserum was produced against synthesized peptide derived from human PRKAG1/2/3. AA range:46-95
- 偶联Non-conjugated
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性能
- 形态Liquid
- 浓度1 mg/mL.
- 存放说明Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
- 存储缓冲液Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- 亚型IgG
- 纯化方式Immunogen affinity purified.
- 其它名称PRKAG1 antibody; 5'-AMP-activated protein kinase subunit gamma-1 antibody; AMPK gamma1 antibody; AMPK subunit gamma-1 antibody; AMPKg antibody; PRKAG2 antibody; 5'-AMP-activated protein kinase subunit gamma-2 antibody; AMPK gamma2 antibody; AMPK subunit gamma-2 antibody; H91620p antibody; PRKAG3 antibody; AMPKG3 antibody; 5'-AMP-activated protein antibody;
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应用
WB: 1:500-1:2000
IF: 1:100-1:500
特别提示：本公司的所有产品仅可用于科研实验，严禁用于临床医疗及其他非科研用途！
