Anti-ATF-6β antibody
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概述
- 产品描述The protein encoded by this gene is a transcription factor in the unfolded protein response (UPR) pathway during ER stress. Either as a homodimer or as a heterodimer with ATF6-alpha, the encoded protein binds to the ER stress response element, interacting with nuclear transcription factor Y to activate UPR target genes. The protein is normally found in the membrane of the endoplasmic reticulum; however, under ER stress, the N-terminal cytoplasmic domain is cleaved from the rest of the protein and translocates to the nucleus. Two transcript variants encoding different isoforms have been found for this gene.
- 产品名称Anti-ATF-6β antibody
- 分子量76 kDa
- 种属反应性Human
- 验证应用WB, IHC-P
- 抗体类型兔多抗
- 免疫原The antiserum was produced against synthesized peptide derived from human ATF6B. AA range:401-450
- 偶联Non-conjugated
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性能
- 形态Liquid
- 浓度1 mg/mL.
- 存放说明Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
- 存储缓冲液Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- 亚型IgG
- 纯化方式Immunogen affinity purified.
- 其它名称ATF6B antibody; CREBL1 antibody; G13 antibody; Cyclic AMP-dependent transcription factor ATF-6 beta antibody; cAMP-dependent transcription factor ATF-6 beta antibody; Activating transcription factor 6 beta antibody; ATF6-beta antibody; Protein G13 antibody; cAMP response element-binding protein-related protein antibody; antibody;
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Fig1: Western Blot analysis of various cells using ATF-6β Polyclonal Antibody
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