Anti-KCNQ2/3/4/5 antibody
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概述
- 产品描述The M channel is a slowly activating and deactivating potassium channel that plays a critical role in the regulation of neuronal excitability. The M channel is formed by the association of the protein encoded by this gene and a related protein encoded by the KCNQ3 gene, both integral membrane proteins. M channel currents are inhibited by M1 muscarinic acetylcholine receptors and activated by retigabine, a novel anti-convulsant drug. Defects in this gene are a cause of benign familial neonatal convulsions type 1 (BFNC), also known as epilepsy, benign neonatal type 1 (EBN1). At least five transcript variants encoding five different isoforms have been found for this gene.
- 产品名称Anti-KCNQ2/3/4/5 antibody
- 种属反应性Human,Mouse,Rat
- 验证应用IHC-P
- 抗体类型兔多抗
- 免疫原The antiserum was produced against synthesized peptide derived from human Kv7.3/KCNQ3. AA range:191-240
- 偶联Non-conjugated
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性能
- 形态Liquid
- 浓度1 mg/mL.
- 存放说明Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
- 存储缓冲液Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- 亚型IgG
- 纯化方式Immunogen affinity purified.
- 其它名称KCNQ2 antibody; Potassium voltage-gated channel subfamily KQT member 2 antibody; KQT-like 2 antibody; Neuroblastoma-specific potassium channel subunit alpha KvLQT2 antibody; Voltage-gated potassium channel subunit Kv7.2 antibody; KCNQ3 antibody; Potassium voltage-gated channel subfamily KQT me antibody;
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