Anti-MSTN antibody [B2-E4]

Anti-MSTN antibody [B2-E4]

• 概述

• 产品描述Growth/differentiation factors (GDFs) are members of the TGF superfamily. Members of the TGF superfamily are involved in embryonic development and adult tissue homeostasis. GDF-8, also known as myostatin, has been shown to be a negative regulator of skeletal muscle growth. GDF-11 has been shown to control anterior/posterior patterning of the axial skeleton, and also regulates kidney and pancreas organogenesis. GDF-11 controls anterior/posterior patterning of the axial skeleton, regulates organogenesis by controlling the expression of GDNF, contributes to the control of HOX gene expression and induces phosphorylation of Smad2. In addition, GDF-11 mediates signaling of Nodal during left-right patterning and development of head structures and inhibits generation of new neurons by neuronal progenitors in the olfactory epithelium.
• 产品名称Anti-MSTN antibody [B2-E4]
• 分子量43 kDa
• 种属反应性Human
• 验证应用WB,IHC-P,FC
• 抗体类型小鼠单抗
• 免疫原Recombinant protein
• 偶联Non-conjugated

• 性能

• 形态Liquid
• 浓度2 mg/mL.
• 存放说明Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
• 存储缓冲液1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
• 亚型IgG2b
• 纯化方式Protein A purified.
• 亚细胞定位Secreted
• 其它名称
  • GDF 8 antibody
  • GDF-8 antibody
  • GDF8 antibody
  more

• 应用

  WB: 1:500-1:2,000
  IHC-P: 1:200-1:1,000
  FC: 1:50-1:100

•  

  

  Fig1: Western blot analysis of GDF8 on human GDF8 recombinant protein using anti- GDF8 antibody at 1/1,000 dilution.

   

  

  Fig2: Western blot analysis of GDF8 on LNcap cell lysate using anti- GDF8 antibody at 1/1,000 dilution.

   

  

  Fig3: Immunohistochemical analysis of paraffin-embedded human cervical cancer tissue using anti- GDF8 antibody. Counter stained with hematoxylin.

   

  

  Fig4: Immunohistochemical analysis of paraffin-embedded human liver cancer tissue using anti- GDF8 antibody. Counter stained with hematoxylin.

   

  

  Fig5: Flow cytometric analysis of LNcap cells with GDF8 antibody at 1/100 dilution (green) compared with an unlabelled control (cells without incubation with primary antibody; red).

特别提示：本公司的所有产品仅可用于科研实验，严禁用于临床医疗及其他非科研用途！