Anti-Ubr1 antibody
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概述
- 产品描述The N-end rule pathway is one proteolytic pathway of the ubiquitin system. The recognition component of this pathway, encoded by this gene, binds to a destabilizing N-terminal residue of a substrate protein and participates in the formation of a substrate-linked multiubiquitin chain. This leads to the eventual degradation of the substrate protein. The protein described in this record has a RING-type zinc finger and a UBR-type zinc finger. Mutations in this gene have been associated with Johanson-Blizzard syndrome.
- 产品名称Anti-Ubr1 antibody
- 分子量36 kDa
- 种属反应性Human, Mouse
- 验证应用WB, IHC-P
- 抗体类型兔多抗
- 免疫原The antiserum was produced against synthesized peptide derived from human UBR1. AA range:821-870
- 偶联Non-conjugated
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性能
- 形态Liquid
- 浓度1 mg/mL.
- 存放说明Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
- 存储缓冲液Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- 亚型IgG
- 纯化方式Immunogen affinity purified.
- 其它名称
- UBR1 antibody; E3 ubiquitin-protein ligase UBR1 antibody; N-recognin-1 antibody; Ubiquitin-protein ligase E3-alpha-1 antibody; Ubiquitin-protein ligase E3-alpha-I antibody;
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应用
WB: 1:500-1:2000
IHC-P: 1:100-1:300
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Fig1: Western Blot analysis of various cells using Ubr1 Polyclonal Antibody diluted at 1：2000. Secondary antibody（catalog#：HA1001) was diluted at 1:20000
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