Anti-Tet1 antibody
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概述
- 产品描述TET1 (tet oncogene 1), also known as LCX or CXXC6, is a 2,136 amino acid protein that localizes to the nucleus and contains one CXXC-type zinc finger. Expressed in adult ovary, thymus and skeletal muscle and also present in fetal lung, heart and brain, TET1 is thought to play a role in the development of fetal organs and may also be involvement in the pathoegenesis and metastasis of acute myeloid leukemia (AML). The gene encoding TET1 maps to human chromosome 10, which houses over 1,200 genes and comprises nearly 4.5% of the human genome. Defects in some of the genes that map to chromosome 10 are associated with Charcot-Marie Tooth disease, Jackson-Weiss syndrome, Usher syndrome, nonsyndromatic deafness, Wolman’s syndrome, Cowden syndrome, multiple endocrine neoplasia type 2 and porphyria.
- 产品名称Anti-Tet1 antibody
- 分子量235kDa
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种属反应性Human,Mouse,Rat
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验证应用IHC-P,FC,ICC
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抗体类型兔多抗
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免疫原Synthetic peptide (KLH-coupled) within human TET1 820-900 aa.
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偶联Non-conjugated
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性能
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形态Liquid
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浓度1 mg/mL.
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存放说明Store at +4℃ after thawing. Aliquot store at -20℃. Avoid repeated freeze / thaw cycles.
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存储缓冲液1*PBS (pH7.4), 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
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亚型IgG
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纯化方式Peptide affinity purified
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亚细胞定位Nucleus
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其它名称
more
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bA119F7.1 antibody
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CXXC 6 antibody
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CXXC finger 6 antibody
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应用
ICC: 1:50-1:200
IHC-P: 1:50-1:200
FC: 1:50-1:100
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Fig1: Immunocytochemical staining of SH-SY-5Y cells using anti-TET1 rabbit polyclonal antibody.
Fig2: Immunohistochemical analysis of paraffin- embedded mouse brain tissue using anti-TET1 rabbit polyclonal antibody.
Fig3: Flow cytometric analysis of SH-SY-5Y cells with TET1 antibody at 1/50 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black). Alexa Fluor 488-conjugated Goat anti rabbit IgG was used as the secondary antibody.
特别提示：本公司的所有产品仅可用于科研实验，严禁用于临床医疗及其他非科研用途！
