Anti-TRAF6 antibody
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概述
- 产品描述TRAF proteins are associated with, and mediate signal transduction from members of the TNF receptor superfamily. This protein mediates the signaling not only from the members of the TNF receptor superfamily, but also from the members of the Toll/IL-1 family. Signals from receptors such as CD40, TNFSF11/TRANCE/RANKL and IL-1 have been shown to be mediated by this protein. This protein also interacts with various protein kinases including IRAK1/IRAK, SRC and PKCzeta, which provides a link between distinct signaling pathways. This protein functions as a signal transducer in the NF-kappaB pathway that activates IkappaB kinase (IKK) in response to proinflammatory cytokines.
- 产品名称Anti-TRAF6 antibody
- 分子量60 kDa
- 种属反应性Human, Mouse, Rat
- 验证应用ICC, IHC-P,WB
- 抗体类型兔多抗
- 免疫原Synthetic peptide within C-terminal human TRAF6.
- 偶联Non-conjugated
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性能
- 形态Liquid
- 浓度1 mg/mL.
- 存放说明Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
- 存储缓冲液1*PBS (pH7.4), 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
- 亚型IgG
- 纯化方式Peptide affinity purified
- 亚细胞定位Cytoplasm, nucleus
- 其它名称
- E3 ubiquitin-protein ligase TRAF6 antibody
- Interleukin 1 signal transducer antibody
- Interleukin-1 signal transducer antibody
more
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应用
WB: 1:500-1:1,000
ICC: 1:100-1:200
WB: 1:500-1:2,000
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Fig1: Western blot analysis on cell lysates using anti-TRAF6 rabbit polyclonal antibodies.
Fig2: ICC staining TRAF6 in Hela cells (green). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
Fig3: Western blot analysis of TRAF6 on hybrid fish (crucian-carp) heart tissue lysate using anti-TRAF6 antibody at 1/500 dilution.
特别提示：本公司的所有产品仅可用于科研实验，严禁用于临床医疗及其他非科研用途！
