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Anti-AXL antibody
产品描述The UFO family of receptor tyrosine kinases is comprised of subfamily members Rse (also designated Tyro3, Sky, Brt, Dtk, Etk2 and Tif), Axl (also designated UFO or ARK) and Mer (also designated Nyk or Eyk). Rse is expressed Preferentially in the adult brain with lower expression in other tissues. Axl is found at highest levels in heart and skeletal muscle. Mer has been identified as a tyrosine kinase is involved in the development of glioblastomas. It is expressed at highest levels in ovary, prostate , Lung and kidney. Gas6, a growth arrest specific gene, and the related anticoagulation factor Protein S, have been identified as ligands for the UFO family of receptors.
产品名称Anti-AXL antibody
分子量98 kDa(Predicted band)
种属反应性Human,Mouse
验证应用WB,ICC
抗体类型兔多抗
免疫原Recombinant protein within human AXL 1-200 aa.
偶联Non-conjugated
形态Liquid
浓度2 mg/ml
存放说明Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
存储缓冲液1*PBS (pH7.4), 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
亚型IgG
纯化方式Protein A purified.
亚细胞定位Membrane.
其它名称
Adhesion related kinase antibody
AI323647 antibody
Ark antibody
WB: 1:500
ICC: 1:50-1:200
Fig1: Western blot analysis of AXL on different lysates using anti-AXL antibody at 1/100 dilution.
Positive control:
Lane 1: Mouse kidney tissue
Lane 2: CRC
Fig2: Western blot analysis of AXL on human AXL recombinant protein using anti-AXL antibody at 1/1,000 dilution.
Fig3: ICC staining AXL in Hela cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
Fig4: ICC staining AXL in LOVO cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
Fig5: ICC staining AXL in MCF-7 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
特别提示：本公司的所有产品仅可用于科研实验，严禁用于临床医疗及其他非科研用途！
