Anti-INHA antibody [C8-E2]

Anti-INHA antibody [C8-E2]

• 概述

• 产品描述Inhibin is a gonadal protein that preferentially suppresses the secretion of pituitary follicle-stimulating hormone (FSH). Inhibin comprises two subunits, Inhibin A and Inhibin B. Each subunit consists of the same α subunit, covalently linked to 1 of 2 distinct subunits, β-α or β-β. Originally isolated from ovarian follicular fluid and characterized as a disulphide-linked dimeric glycoprotein, inhibin belongs to the transforming growth factor β (TGFβ) superfamily of growth and differentiation factors. TGFβ proteins affect a range of tissues and systems beyond their role in reproduction. In addition to their role in endocrine feedback in the reproductive sytem, inhibins subserve local regulatory roles in numerous extragonadal tissues, including brain, adrenal, bone marrow, placenta and, most notably, anterior pituitary. Inhibin α-subunit gene expression is down regulated in human prostate cancer, suggesting a tumor-suppressive role. The human Inhibin α gene maps to chromosome 2q33-q36.
• 产品名称Anti-INHA antibody [C8-E2]
• 分子量40 kDa
• 种属反应性Human,Mouse
• 验证应用WB,ICC
• 抗体类型小鼠单抗
• 免疫原Recombinant protein
• 偶联Non-conjugated

• 性能

• 形态Liquid
• 浓度2 mg/mL.
• 存放说明Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
• 存储缓冲液1*TBS (pH7.4), 1%BSA, Preservative: 0.05% Sodium Azide.
• 亚型IgG1
• 纯化方式Protein A purified.
• 亚细胞定位Secreted.
• 其它名称
  • A inhibin subunit antibody
  • A inhibin subunit precursor antibody
  • AW55578 antibody
  more

• 应用

  WB: 1:500-1:1,000
  ICC: 1:50-1:200

•  

  

  Fig1: Western blot analysis of INHA on mouse spermary tissue lysate using anti-INHA antibody at 1/1,000 dilution.

   

  

  Fig2: ICC staining INHA (green) and actin filaments (red) in PANC-1 cells. The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.

特别提示：本公司的所有产品仅可用于科研实验，严禁用于临床医疗及其他非科研用途！