Anti-CCDC47 antibody [1-B9-5]

Anti-CCDC47 antibody [1-B9-5] 

• 概述

• 产品描述Coiled-coil domain 47 (CCDC47) is a gene located on human chromosome 17, specifically locus 17q23.3 which encodes for the protein CCDC47. The gene has several aliases including GK001 and MSTP041. The protein itself contains coiled-coil domains, the SEEEED superfamily, a domain of unknown function (DUF1682) and a transmembrane domain. The function of the protein is unknown, but it has been proposed that CCDC47 is involved in calcium ion homeostasis and the endoplasmic reticulum overload response. In addition to the high levels of phosphorylation seen in CCDC47, three sulfination sites are predicted and conserved in mammals, reptiles and birds but not in fish, amphibians or invertebrates. Five potential sumoylation sites are also seen and conserved back to the bony fish. There is no glycosylation of the protein as it is not predicted to extend into the extracellular portion of the cell.
• 产品名称Anti-CCDC47 antibody [1-B9-5]
• 分子量56 kDa
• 种属反应性Human,Mouse
• 验证应用ICC,IHC-P
• 抗体类型小鼠单抗
• 免疫原Recombinant protein
• 偶联Non-conjugated

• 性能

• 形态Liquid
• 浓度2 mg/mL.
• 存放说明Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
• 存储缓冲液1*PBS (pH7.4), 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
• 亚型IgG1
• 亚细胞定位Membrane, nucleus.
• 其它名称
  • CCD47_HUMAN antibody
  • CCDC 47 antibody
  • CCDC47 antibody
  more

• 应用

  WB: 1:500-1:1,000
  ICC: 1:50-1:200
  IHC-P: 1:50-1:200

•  

  

  Fig1: Western blot analysis of CCDC47 on recombinant protein using anti-CCDC47 antibody at 1/1,000 dilution.

   

  

  Fig2: ICC staining CCDC47 in F9 cells (red). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.

   

  

  Fig3: ICC staining CCDC47 in MCF-7 cells (red). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.

   

  

  Fig4: Immunohistochemical analysis of paraffin-embedded human lung tissue using anti-CCDC47 antibody. Counter stained with hematoxylin.

   

  

  Fig5: Immunohistochemical analysis of paraffin-embedded human liver tissue using anti-CCDC47 antibody. Counter stained with hematoxylin.

   

  

  Fig6: Immunohistochemical analysis of paraffin-embedded human testis tissue using anti-CCDC47 antibody. Counter stained with hematoxylin.

   

  

  Fig7: Immunohistochemical analysis of paraffin-embedded human colon tissue using anti-CCDC47 antibody. Counter stained with hematoxylin.

   

  

  Fig8: Immunohistochemical analysis of paraffin-embedded human breast tissue using anti-CCDC47 antibody. Counter stained with hematoxylin.

   

  

  Fig9: Immunohistochemical analysis of paraffin-embedded human stomach tissue using anti-CCDC47 antibody. Counter stained with hematoxylin.

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