Anti-PODXL antibody [D0-E8]

Anti-PODXL antibody [D0-E8]

• 概述

• 产品描述Podocalyxin, a sialoglycoprotein, is thought to be the major constituent of the glycocalyx of podocytes. It is a member of the CD34 family of transmembrane sialomucins. It is involved in the regulation of both adhesion and cell morphology and cancer progression. It functions as an anti-adhesive molecule that maintains an open filtration pathway between neighboring foot processes in the podocyte by charge repulsion. Podocalyxin acts as a pro-adhesive molecule, enhancing the adherence of cells to immobilized ligands, increasing the rate of migration and cell-cell contacts in an integrin-dependent manner. Sialylated, O-glycosylated glycoforms of podocalyxin expressed by colon carcinoma cells possess L-selectin and E-selectin binding activity, and may be pivotal to the metastatic spread of colon carcinoma cells
• 产品名称Anti-PODXL antibody [D0-E8]
• 分子量58kDa
• 种属反应性Human
• 验证应用WB
• 抗体类型小鼠单抗
• 免疫原recombinant protein
• 偶联Non-conjugated

• 性能

• 形态Liquid
• 浓度2 mg/mL.
• 存放说明Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
• 存储缓冲液1*PBS (pH7.4), 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
• 亚型IgG1
• 纯化方式Protein G purified.
• 亚细胞定位Apical cell membrane
• 其它名称
  • GCTM-2 antigen antibody
  • Gp2 antibody
  • Gp200 antibody
  more

• 应用

  WB 1:2,000-1:5,000

•  

  

  Fig1: Western blot analysis on cell lysates using anti- PODXL Mouse mAb.

特别提示：本公司的所有产品仅可用于科研实验，严禁用于临床医疗及其他非科研用途！