Anti-Complement C3(β- chain) antibody [11-10]

Anti-Complement C3(β- chain) antibody [11-10]

• 概述

• 产品描述Human Complement C3 (C3) is synthesized as a single-chain pro-molecule (185 kDa) that tsuffers several posttranslational modifications. Before being a mature protein, C3 is split into beta-chain (70 kDa) and alpha chain (115 kDa) and forms a rare internal thioester bond. C3 plays a central role in the activation of the complement system. It’s processing by C3 convertase is the central reaction in both classical and alternative complement pathways. After activation C3b can bind covalently, via its reactive thioester, to cell surface carbohydrates or immune aggregates.
• 产品名称Anti-Complement C3(β- chain) antibody [11-10]
• 分子量70kDa
• 种属反应性Human
• 验证应用WB,ICC,FC
• 抗体类型小鼠单抗
• 免疫原peptide
• 偶联Non-conjugated

• 性能

• 形态Liquid
• 浓度2 mg/mL.
• 存放说明Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
• 存储缓冲液1*PBS (pH7.4), 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
• 亚型IgG2b
• 纯化方式Protein A purified.
• 亚细胞定位secrete
• 其它名称
  • Acylation-stimulating protein cleavage product antibody
  • AHUS5 antibody
  • ARMD9 antibody
  more

• 应用

  WB: 1:2,000

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  Fig1: Western blot analysis on human plasma lysates using anti-C3(β-chain) Mouse mAb (Cat. # M0809-14).

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