Anti-ApoE antibody
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概述
- 产品描述Apolipoprotein-E (apoE) is a protein component of plasma lipoproteins. Three common ApoE alleles have been identified: ApoE2, ApoE3, and ApoE4. The corresponding three major isoforms, E2, E3, and E4, are recognized according to their relative position after isoelectric focusing. ApoE mediates the binding, internalization, and catabolism of lipoprotein particles. It can serve as a ligand for the LDL (Apo B/E) receptor and for the specific Apo-E receptor (chylomicron remnant) of hepatic tissues. Defects in Apolipoprotein E result in familial dysbetalipoproteinemia, or type III hyperlipoproteinemia (HLP III), in which increased plasma cholesterol and triglycerides are the consequence of impaired clearance of chylomicron and VLDL remnants.
- 产品名称Anti-ApoE antibody
- 分子量36 kDa
- 种属反应性Human
- 验证应用WB
- 抗体类型兔多抗
- 免疫原peptide
- 偶联Non-conjugated
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性能
- 形态Liquid
- 浓度1 mg/mL.
- 存放说明Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
- 存储缓冲液1*PBS (pH7.4), 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
- 亚型IgG
- 纯化方式Immunogen affinity purified
- 亚细胞定位Secretory protein
- 其它名称AD2 antibody
Apo-E antibody
APOE antibody
APOE_HUMAN antibody
APOEA antibody
Apolipoprotein E antibody
Apolipoprotein E3 antibody
ApolipoproteinE antibody
Apoprotein antibody
LDLCQ5 antibody
LPG antibody
more
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Fig1: Western blot analysis on human liver using anti-ApoE polyclonal antibody.
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