Anti-CDO1 antibody
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概述
- 产品描述catalytic activity:L-cysteine + O(2) = 3-sulfinoalanine. cofactor:Binds 1 iron ion per subunit. Zinc to a much lesser extent. cofactor:IRON; NAD(P)H. Initiates several important metabolic pathways related to pyruvate and several sulfurate compounds including sulfate, hypotaurine and taurine. Critical regulator of cellular cysteine concentrations. Has an important role in maintaining the hepatic concentation of intracellular free cysteine within a proper narrow range. induction:In hepatoblastoma HepG2 cells, down-regulated by phorbol 12-myristate 13-acetate. pathway:Organosulfur biosynthesis; taurine biosynthesis; hypotaurine from L-cysteine: step 1/2. PTM:The thioether cross-link between Cys-93 and Tyr-157 plays a structural role through stabilizing the Fe(2+) ion, and prevents the production of highly damaging free hydroxyl radicals by holding the oxygen radical via hydroxyl hydrogen. Belongs to the cysteine dioxygenase family. subunit:Monomer. tissue specificity:Highly expressed in liver and placenta. Low expression in heart, brain and pancreas. Also detected in hepatoblastoma HepG2 cells.
- 产品名称Anti-CDO1 antibody
- 分子量22 kDa
- 种属反应性Human,Mouse,Rat
- 验证应用WB
- 抗体类型兔多抗
- 免疫原Synthesized peptide derived from part region of human protein
- 偶联Non-conjugated
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性能
- 形态Liquid
- 浓度1 mg/mL.
- 存放说明Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
- 存储缓冲液Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
- 亚型IgG
- 纯化方式Immunogen affinity purified.
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特别提示：本公司的所有产品仅可用于科研实验，严禁用于临床医疗及其他非科研用途！
