Anti-Abi-1 antibody
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概述
- 产品描述This gene encodes a member of the Abelson-interactor family of adaptor proteins. These proteins facilitate signal transduction as components of several multiprotein complexes, and regulate actin polymerization and cytoskeletal remodeling through interactions with Abelson tyrosine kinases. The encoded protein plays a role in macropinocytosis as a component of the WAVE2 complex, and also forms a complex with EPS8 and SOS1 that mediates signal transduction from Ras to Rac. This gene may play a role in the progression of several malignancies including melanoma, colon cancer and breast cancer, and a t(10;11) chromosomal translocation involving this gene and the MLL gene has been associated with acute myeloid leukemia. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 14. [provided by RefSeq
- 产品名称Anti-Abi-1 antibody
- 分子量55 kDa
- 种属反应性Human, Mouse, Rat
- 验证应用WB
- 抗体类型兔多抗
- 免疫原The antiserum was produced against synthesized peptide derived from human Abi-1. AA range:152-201
- 偶联Non-conjugated
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性能
- 形态Liquid
- 浓度1 mg/mL.
- 存放说明Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
- 存储缓冲液Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- 亚型IgG
- 纯化方式Immunogen affinity purified.
- 其它名称ABI1 antibody; SSH3BP1 antibody; Abl interactor 1 antibody; Abelson interactor 1 antibody; Abi-1 antibody; Abl-binding protein 4 antibody; AblBP4 antibody; Eps8 SH3 domain-binding protein antibody; Eps8-binding protein antibody; Nap1-binding protein antibody; Nap1BP antibody; Spectrin SH3 domain-binding protein 1 antibody; e3B1 antibody;
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Fig1: Western Blot analysis of various cells using Abi-1 Polyclonal Antibody
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