Anti-ERI1 antibody
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概述
- 产品描述cofactor:Binds 2 magnesium ions per subunit. enzyme regulation:Although it can bind simultaneously with SLBP to the 3'-end of histone mRNA, the presence of SLBP prevents the exonuclease activity. RNA exonuclease that binds to the 3'-end of histone mRNAs and probably degrades them, suggesting that it plays an essential role in histone mRNA decay after replication. Also able to degrade the 3'-overhangs of short interfering RNAs (siRNAs) in vitro, suggesting a possible role as regulator of RNA interference (RNAi). Required for 5. 8S rRNA 3'-end processing. sequence caution:Translated as Leu. Contains 1 exonuclease domain. Contains 1 SAP domain. subunit:Binds with high affinity to the stem-loop structure of replication-dependent histone pre-mRNAs. Requires the 5'-ACCCA-3' sequence present in stem-loop structure. Able to bind other mRNAs. Binds to 40S and 60S ribosomal subunits and to 80S assembled ribosomes. Also binds to 5. 8s ribosomal RNA.
- 产品名称Anti-ERI1 antibody
- 分子量37 kDa
- 种属反应性Human,Mouse,Rat
- 验证应用WB
- 抗体类型兔多抗
- 免疫原The antiserum was produced against synthesized peptide derived from human ERI1. AA range:261-310
- 偶联Non-conjugated
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性能
- 形态Liquid
- 浓度1 mg/mL.
- 存放说明Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
- 存储缓冲液Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- 亚型IgG
- 纯化方式Immunogen affinity purified.
- 其它名称ERI1 antibody; 3'EXO antibody; THEX1 antibody; 3'-5' exoribonuclease 1 antibody; 3'-5' exonuclease ERI1 antibody; Eri-1 homolog antibody; Histone mRNA 3'-end-specific exoribonuclease antibody; Histone mRNA 3'-exonuclease 1 antibody; Protein 3'hExo antibody; HEXO antibody;
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特别提示：本公司的所有产品仅可用于科研实验，严禁用于临床医疗及其他非科研用途！
