Anti-DAAM1 antibody
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概述
- 产品描述Cell motility, adhesion, cytokinesis, and other functions of the cell cortex are mediated by reorganization of the actin cytoskeleton and several formin homology (FH) proteins have been associated with these processes. The protein encoded by this gene contains two FH domains and belongs to a novel FH protein subfamily implicated in cell polarity. A key regulator of cytoskeletal architecture, the small GTPase Rho, is activated during development by Wnt/Fz signaling to control cell polarity and movement. The protein encoded by this gene is thought to function as a scaffolding protein for the Wnt-induced assembly of a disheveled (Dvl)-Rho complex. This protein also promotes the nucleation and elongation of new actin filaments and regulates cell growth through the stabilization of microtubules. Alternative splicing results in multiple transcript variants encoding distinct
- 产品名称Anti-DAAM1 antibody
- 分子量123 kDa
- 种属反应性Human, Mouse
- 验证应用WB
- 抗体类型兔多抗
- 免疫原Synthetic peptide from human protein at AA range: 400-500
- 偶联Non-conjugated
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性能
- 形态Liquid
- 浓度1 mg/mL.
- 存放说明Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
- 存储缓冲液Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- 亚型IgG
- 纯化方式Immunogen affinity purified.
- 其它名称
- Disheveled-associated activator of morphogenesis 1 antibody;
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Fig1: Western blot analysis of SW480 MCF7 lysate, antibody was diluted at 500. Secondary antibody(catalog#:HA1001) was diluted at 1:20000
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