Anti-TSH antibody [AH21-10]

Anti-TSH antibody [AH21-10] 

• 概述

• 产品描述Various hormones are secreted from the anterior pituitary during development and growth, including thyroid-stimulating hormone (TSH, also known as thyrotropin), follicle-stimulating hormone (FSH) and leutinizing hormone (LH). TSH, FSH, and LH are heterodimers formed from a common α chain and a unique β chain. TSH is a glycoprotein involved in the control of thyroid structure and metabolism, which stimulates the release of the thyroid hormones. TSHβ is regulated by thyroid hormone (T3) and various retinoid compounds. TSHβ binds to the thyroid-stimulating hormone receptor (TSHR), which plays a major role in regulating thyroid function. TSHR is thought to exist in multiple glycosylation states. The third cytoplasmic loop of TSHR has been identified as critical for its role in regulating inositol phosphate and cAMP formation.
• 产品名称Anti-TSH antibody [AH21-10]
• 分子量42 kDa
• 种属反应性Human,Mouse
• 验证应用ELISA,WB,IHC-P,ICC
• 抗体类型小鼠单抗
• 免疫原recombinant protein
• 偶联Non-conjugated

• 性能

• 形态Liquid
• 浓度2 mg/mL.
• 存放说明Store at -20 ℃. Stable for 12 months from date of receipt.
• 存储缓冲液1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.23% Sodium Azide.
• 亚型IgG1
• 亚细胞定位Secreted.
• 其它名称
  • CG ALPHA antibody
  • CGA antibody
  • Chorionic gonadotropin alpha polypeptide antibody
  more

• 应用

  WB: 1:1,000
  ICC: 1:50-1:200
  IHC-P: 1:50-1:200
  ELISA: 1:5,000-1:10,000

•  

  

  Fig1: ICC staining TSH in HepG2 cells (red). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.

   

  

  Fig2: ICC staining TSH in JAR cells (red). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.

   

  

  Fig3: Immunohistochemical analysis of paraffin-embedded mouse placenta tissue using anti-TSH antibody. Counter stained with hematoxylin.

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