Anti-CD16 antibody [Q32]

Anti-CD16 antibody [Q32]

• 概述

• 产品描述This gene encodes a receptor for the Fc portion of immunoglobulin G, and it is involved in the removal of antigen-antibody complexes from the circulation, as well as other other antibody-dependent responses. This gene (FCGR3A) is highly similar to another nearby gene (FCGR3B) located on chromosome 1. The receptor encoded by this gene is expressed on natural killer (NK) cells as an integral membrane glycoprotein anchored through a transmembrane peptide, whereas FCGR3B is expressed on polymorphonuclear neutrophils (PMN) where the receptor is anchored through a phosphatidylinositol (PI) linkage. Mutations in this gene have been linked to susceptibility to recurrent viral infections, susceptibility to systemic lupus erythematosus, and alloimmune neonatal neutropenia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq,
• 产品名称Anti-CD16 antibody [Q32]
• 分子量45 kDa
• 种属反应性Human
• 验证应用WB, IHC-P
• 抗体类型小鼠单抗
• 免疫原Synthetic Peptide of CD16
• 偶联Non-conjugated

• 性能

• 形态Liquid
• 浓度1 mg/mL.
• 存放说明Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
• 存储缓冲液PBS, pH 7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol.
• 亚型IgG1
• 纯化方式Immunogen affinity purified.
• 亚细胞定位Cell membrane, Secreted.
• 其它名称
  • CD 16 antibody
  • CD 16a antibody
  • CD16 antibody
  more

• 应用

  WB: 1:1000
  IHC-P: 1:50-300

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  Fig1: Immunohistochemical analysis of paraffin-embedded Human-liver tissue. 1,CD16 Monoclonal Antibody(Q32) was diluted at 1:200(4°C,overnight). 2, Sodium citrate pH 6.0 was used for antibody retrieval(>98°C,20min). 3,Secondary antibody was diluted at 1:200(room tempeRature, 30min). Negative control was used by secondary antibody only.

   

  

  Fig2: Western blot analysis of 1) Jurkat, 2) K562, diluted at 1:2000

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