Anti-ATG13 antibody [E12-B2]

Anti-ATG13 antibody [E12-B2]

• 概述

• 产品描述Autophagy factor required for autophagosome formation and mitophagy. Target of the TOR kinase signaling pathway that regulates autophagy through the control of the phosphorylation status of ATG13 and ULK1, and the regulation of the ATG13-ULK1-RB1CC1 complex. Through its regulation of ULK1 activity, plays a role in the regulation of the kinase activity of mTORC1 and cell proliferation.
• 产品名称Anti-ATG13 antibody [E12-B2]
• 分子量56 kDa
• 种属反应性Human
• 验证应用WB,IHC-P
• 抗体类型小鼠单抗
• 免疫原Recombinant protein
• 偶联Non-conjugated

• 性能

• 形态Liquid
• 浓度2 mg/mL.
• 存放说明Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
• 存储缓冲液1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
• 亚型IgG1
• 纯化方式Protein A purified.
• 亚细胞定位Cytoplasm
• 其它名称
  • ATG13 antibody
  • ATG13 autophagy related 13 homolog (S. cerevisiae) antibody
  • ATG13_HUMAN antibody
  more

• 应用

  WB: 1:500-1:2,000
  IHC-P: 1:50-1:200

•  

  

  Fig1: Western blot analysis of ATG13 on human ATG13 recombinant protein using anti-ATG13 antibody at 1/1,000 dilution.

   

  

  Fig2: Western blot analysis of ATG13 on HEK293 (1) and ATG13-hIgGFc transfected HEK293 (2) cell lysate using anti-ATG13 antibody at 1/1,000 dilution.

   

  

  Fig3: Immunohistochemical analysis of paraffin-embedded human striated muscle tissue using anti-ATG13 antibody. Counter stained with hematoxylin.

   

  

  Fig4: Immunohistochemical analysis of paraffin-embedded human cardiac muscle tissue using anti-ATG13 antibody. Counter stained with hematoxylin

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