Anti-TRPM5 antibody
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概述
- 产品描述Voltage-modulated Ca(2+)-activated, monovalent cation channel (VCAM) that mediates a transient membrane depolarization and plays a central role in taste transduction. Monovalent-specific, non-selective cation channel that mediates the transport of Na(+), K(+) and Cs(+) ions equally well. Activated directly by increases in intracellular Ca(2+), but is impermeable to it. Gating is voltage-dependent and displays rapid activation and deactivation kinetics upon channel stimulation even during sustained elevations in Ca(2+). Also activated by a fast intracellular Ca(2+) increase in response to inositol 1,4,5-triphosphate-producing receptor agonists. The channel is blocked by extracellular acidification. External acidification has 2 effects, a fast reversible block of the current and a slower irreversible enhancement of current inactivation. Is a highly temperature-sensitive, heat activated channel showing a steep increase of inward currents at temperatures between 15 and 35 degrees Celsius. Heat activation is due to a shift of the voltage-dependent activation curve to negative potentials. Activated by arachidonic acid in vitro. May be involved in perception of bitter, sweet and umami tastes. May also be involved in sensing semiochemicals.
- 产品名称Anti-TRPM5 antibody
- 分子量131 KDa
- 种属反应性Human,Mouse,Rat,Cow
- 验证应用WB
- 抗体类型兔多抗
- 免疫原KLH conjugated synthetic peptide derived from human TRPM5 701-800/1165
- 偶联Non-conjugated
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性能
- 形态Liquid
- 浓度1 mg/mL.
- 存放说明Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20℃. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4℃.
- 存储缓冲液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 亚型IgG
- 纯化方式affinity purified by Protein A
- 亚细胞定位Cell membrane
- 其它名称MLSN1 and TRP related gene 1
MLSN1 and TRP related gene 1 protein
MLSN1 and TRP-related
MLSN1- and TRP-related gene 1 protein
MTR1
Novel protein similar to vertebrate transient receptor potential cation channel, subfamily M, member 5
Transient receptor potential cation channel subfamily M member 5
Transient receptor potential cation channel, subfamily M, member 5
Trpm5
TRPM5 transient receptor potential cation channel, subfamily M, member 5
TRPM5_HUMAN
9430099A16Rik
Long transient receptor potential channel 5
LTrpC-5
LTrpC5.
more
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Fig1: Sample:
Liver(Human) Cell Lysate at 40 ug
Primary: Anti-TRPM5 at 1/300 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 131 kD
Observed band size: 131 kD
特别提示：本公司的所有产品仅可用于科研实验，严禁用于临床医疗及其他非科研用途！
