Anti-CYP2A6 antibody
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概述
- 产品描述This gene, CYP2A6, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by phenobarbital. The enzyme is known to hydroxylate coumarin, and also metabolizes nicotine, aflatoxin B1, nitrosamines, and some pharmaceuticals. Individuals with certain allelic variants are said to have a poor metabolizer phenotype, meaning they do not efficiently metabolize coumarin or nicotine. This gene is part of a large cluster of cytochrome P450 genes from the CYP2A, CYP2B and CYP2F subfamilies on chromosome 19q. The gene was formerly referred to as CYP2A3; however, it has been renamed CYP2A6.
- 产品名称Anti-CYP2A6 antibody
- 分子量56 kDa
- 种属反应性Human
- 验证应用WB, IF
- 抗体类型兔多抗
- 免疫原The antiserum was produced against synthesized peptide derived from human Cytochrome P450 2A6. AA range:1-50
- 偶联Non-conjugated
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性能
- 形态Liquid
- 浓度1 mg/mL.
- 存放说明Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
- 存储缓冲液Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- 亚型IgG
- 纯化方式Immunogen affinity purified.
- 其它名称CYP2A6 antibody; CYP2A3 antibody; Cytochrome P450 2A6 antibody; 1 antibody; 4-cineole 2-exo-monooxygenase antibody; CYPIIA6 antibody; Coumarin 7-hydroxylase antibody; Cytochrome P450 IIA3 antibody; Cytochrome P450(I) antibody;
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应用
WB: 1:500-1:2000
IF: 1:100-1:500
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Fig1: Western Blot analysis of PC-12 cells using CYP2A6 Polyclonal Antibody diluted at 1:1000
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