Anti-DR3 antibody
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概述
- 产品描述The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is expressed preferentially in the tissues enriched in lymphocytes, and it may play a role in regulating lymphocyte homeostasis. This receptor has been shown to stimulate NF-kappa B activity and regulate cell apoptosis. The signal transduction of this receptor is mediated by various death domain containing adaptor proteins. Knockout studies in mice suggested the role of this gene in the removal of self-reactive T cells in the thymus. Multiple alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported, most of which are potentially secreted molecules. The alternative splicing of this gene in B and T cells encounters a programmed change upon T-cell activation, which predominantly produces full-length, membrane bound isoforms, and is thought to be involve
- 产品名称Anti-DR3 antibody
- 分子量45 kDa
- 种属反应性Human
- 验证应用WB, IHC-P
- 抗体类型兔多抗
- 免疫原Synthesized peptide derived from DR3 . at AA range: 230-310
- 偶联Non-conjugated
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性能
- 形态Liquid
- 浓度1 mg/mL.
- 存放说明Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
- 存储缓冲液Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- 亚型IgG
- 纯化方式Immunogen affinity purified.
- 其它名称
- TNFRSF25 antibody; APO3 antibody; DDR3 antibody; DR3 antibody; TNFRSF12 antibody; WSL antibody; WSL1 antibody; Tumor necrosis factor receptor superfamily member 25 antibody; Apo-3 antibody; Apoptosis-inducing receptor AIR antibody;Apoptosis-mediating receptor DR3 antibody; Apoptosis-mediating receptor TRAMP antibody; Death receptor 3 antibody; Lymphocyte-associated receptor of death antibody; LARD antibody; Protein WSL antibody; Protein WSL-1 antibody;
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应用
WB: 1:500-1:2000
IHC-P: 1:100-300
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Fig1: Western Blot analysis of K562 cells using DR3 Polyclonal Antibody.. Secondary antibody（catalog#：HA1001) was diluted at 1:20000
Fig2: Immunohistochemical analysis of paraffin-embedded human-heart, antibody was diluted at 1:100
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