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ClinMax™Human Interleukin 4 (IL-4) Quantitative ELISA Kit
ClinMax™Human IL-4 Quantitative ELISA Kit is designed to quantitate human IL-4 that is present in complex biological matrices, such as human serum, plasma, buffered solution, or cell culture. IL-4 is a cytokine with pleiotropic functions. IL-4 plays a key role in the development of Th2 responses. In mice that lack IL-4, there is significant abrogation of Th2 cellular activity. IL-4 promotes the growth and activation of B lymphocytes that produce IgG1 and IgE classes of antibodies and increases MHC class II induction. Preclinical animal models have demonstrated modest antitumor efficacy for IL-4. In the nonimmunogenic B16 murine melanoma model, irradiated B16 cells engineered to express IL-4 induced antitumor protection against a wild-type B16 challenge.
This immunoassay is designed to quantitate human IL-4 that is present in human serum, plasma, buffered solution, or cell culture. It has been calibrated against a highly purified human IL-4 and is evaluated with standard from NIBSC/WHO. Reference Reagent Interleukin-4 (Human, rDNA derived) NIBSC code: 88/656.
It is for research use only.
The unopened kit is stable for 12 months from the date of manufacture if stored at 2°C to 8°C. The opened kit should be stored per components table. The shelf life is 30 days from the date of opening.
